Carlo Ancelotti's Everton will welcome Pep Guardiola's Manchester City to Goodison Park in the FA Cup quarter-finals in the pick of the draw.
Manchester United will also travel toPremier League top four rivals Leicester City, while there's a south coast derby between Bournemouth and Southampton.
Chelsea will face relegation-battlers Sheffield United as Thomas Tuchel seeks to continue a strong start to life at Stamford Bridge.
The games will be played in the week of March 20 with kick off times yet to be confirmed.
FA Cup quarter-final draw in full
Everton vs Manchester City
Bournemouth vs Southampton
Leicester City vs Manchester United
Chelsea vs Sheffield United